https://thepatrickwatsonlab.com/features daily 0.75 2020-03-31 https://images.squarespace-cdn.com/content/v1/54061d7fe4b0ee7f1c8414eb/1446741811992-YDCCCNSX7RGCJS7VLVOB/image-asset.jpeg Features - Engineered to Impress The Fulton Cycle is more than just a bike – it's a stunning piece of product design that you'd be proud to ride around the city. Duis mollis, est non commodo luctus, nisi erat porttitor ligula, eget lacinia odio sem nec elit. Vivamus sagittis lacus vel augue laoreet rutrum faucibus dolor auctor. Sed posuere consectetur est. Watch the Video https://images.squarespace-cdn.com/content/v1/54061d7fe4b0ee7f1c8414eb/1446741811992-YDCCCNSX7RGCJS7VLVOB/image-asset.jpeg Features - Engineered to Impress The Fulton Cycle is more than just a bike – it's a stunning piece of product design that you'd be proud to ride around the city. Duis mollis, est non commodo luctus, nisi erat porttitor ligula, eget lacinia odio sem nec elit. Vivamus sagittis lacus vel augue laoreet rutrum faucibus dolor auctor. Sed posuere consectetur est. Watch the Video https://images.squarespace-cdn.com/content/v1/54061d7fe4b0ee7f1c8414eb/1446741831850-SN75S8MNG8T7JM53TW82/IMG_4030.jpg Features - Quality Components We used only the finest materials and components to build the Fulton Cycle. Nullam quis risus eget urna mollis ornare vel eu leo. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Curabitur blandit tempus porttitor. Fusce dapibus, tellus ac cursus commodo, tortor mauris condimentum nibh, ut fermentum. Frequently Asked Questions https://images.squarespace-cdn.com/content/v1/54061d7fe4b0ee7f1c8414eb/1446741849905-XZOW8H9LRB478TF100EQ/IMG_4011-1.jpg Features - Crafted with Love Our goal is not to sell bikes – it's to craft them. Everyone who worked on the Fulton Cycle shares a passion for biking. Curabitur blandit tempus porttitor. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Integer posuere erat a ante venenatis dapibus posuere velit aliquet. Cras justo odio, dapibus ac facilisis in. Nulla vitae elit libero. Meet the Team https://thepatrickwatsonlab.com/photos daily 0.75 2025-10-22 https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1747266825148-0EFADTW7ZH7V1BCNJ1WA/image-asset.jpg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1761164722584-3ZPXR2013WNVZWVSHBDW/image-asset.jpeg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1759279874228-2VAEUDWODNTSHICQVCS5/image-asset.jpeg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1759279988526-GBHVZAY7NY6N3GV323Y9/IMG_1517.jpg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1749171384210-TQSA6PRRYG8T6FFDBCI0/image-asset.jpeg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1749171340714-Z7MUZ736DR3C74ZUTCS0/image-asset.jpeg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1747266886297-S9XPHXEEK708K4FXH2AH/image-asset.jpeg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1744471204312-ZZASDCP6RUKWGOPHX68D/IMG_2426.jpg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1744471200347-6XBV9966FXB4C35FQTC3/IMG_2423.jpg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1744330317773-OXT1R55O539VQCXLJ6NG/IMG_3358.jpg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1744330390415-8X8KJWURPS0DEVFHAKMX/IMG_4503+2.jpg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1744329124049-OGG1V0IVZO6EKOSYJWSI/Lab+Nashville+pic.jpg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1744329465777-35H3PMUJD2IXG7KZKWGG/PW+lab+Escape.jpeg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1744329505600-19MTS4B8KD2BO17FYU4R/Patrick+lab.jpeg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1744329540071-WSI0O9YM6YBV5UVT82OF/Watson+lab.jpeg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1744329234431-H3OPKGZ2CKB6RGWFJKFW/image-asset.jpeg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1744329380800-5SZV3S3MPV8P4UZGSNWH/IMG_6199.JPG Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1744330058983-V77UV0RWIBDK5HNBSQKH/IMG_1931.jpeg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1744330077285-M4JUZ220QWU4WQSJD67N/IMG_4383.JPG Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1744330185377-K3LTXE3UC2RI13N9I0S2/IMG_2888.JPG Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1744330091307-H046QWENOTYYKOXO3CSH/IMG_2882.jpeg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1744330548176-VZHVJCNGTXJSCQ5BH671/IMG_1227+%281%29.JPG Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1744330562604-90XGNAL1T7LYWBQGFQE4/IMG_6655.JPG Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1744330576888-L6TADWLFWD9LEBTV02W5/C2670310-FD9E-4BEA-B729-25D17802E49F.jpg Photos https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1744330590761-7R9R1TQID3M5E8XNX2SE/IMG_1772.jpeg Photos https://thepatrickwatsonlab.com/contact daily 0.75 2025-02-27 https://thepatrickwatsonlab.com/publications daily 0.75 2025-10-10 https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1629914517134-AXAM2F04MBKBM081I0B6/Screen+Shot+2021-08-25+at+12.56.12+PM.png Publications - Global transcriptomics uncovers distinct contributions from splicing regulatory proteins to the macrophage innate immune response Wagner, Scott, West et al., Frontiers in Immunology https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1629914627666-B4LTQBA13KLFZ1Z6CZV6/Screen+Shot+2021-08-25+at+12.57.20+PM.png Publications - Galectin-8 senses phagosomal damage and recruits selective autophagy adapter Tax1BP1 to control Mycobacterium tuberculosis infection in macrophages Bell et al., mBio https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1586370223368-G0MQN3RADN13TBDDGM5W/Screen%2BShot%2B2020-04-08%2Bat%2B1.12.54%2BPM.jpg Publications - The ubiquitin ligase parkin mediates resistance to intracellular pathogens (Watson) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1586372117156-B2LIYNYUOB8LAJEZRUH3/Screen%2BShot%2B2020-04-08%2Bat%2B1.54.25%2BPM.jpg Publications - Sexual dimorphism in campylobacteriosis (Watson) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1586371502742-S8GTPFKQDLIF38ODN2HG/Screen%2BShot%2B2020-04-08%2Bat%2B1.37.06%2BPM.jpg Publications - Campylobacter jejuni survives within epithelial cells by avoiding delivery to lysososomes (Watson) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1586373304992-0MROCZJQWPJ4K9YIWVGH/Screen%2BShot%2B2020-04-08%2Bat%2B2.00.14%2BPM.jpg Publications - Unique features of a highly pathogenic Campylobacter jejuni strain (Watson) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1585757855902-HGGCAIFPK0FV76RL94QZ/Screen%2BShot%2B2020-04-01%2Bat%2B11.16.28%2BAM.jpg Publications - The cytosolic sensor cGAS detects Mycobacterium tuberculosis DNA to induce type I interferons and activate autophagy (Watson) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1586370668786-8TD0OK6VKL2GN4MOK319/image-asset.jpeg Publications - Hierarchal modularity and the evolution of genetic interactomes across species (Patrick) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1585756906654-OGK2M40M9V0WLVFWIOL1/Screen%2BShot%2B2020-04-01%2Bat%2B10.54.40%2BAM.jpg Publications - Exploring the “multiple-hit hypothesis” of neurodegenerative disease: bacterial infection comes up to bat Patrick et al., Frontiers in Cellular and Infection Microbiology https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1586371997886-2PV42PDVYRTDMWKG2ZY3/Screen+Shot+2020-04-08+at+1.52.11+PM.png Publications - Genomic rearrangements and transcriptional analysis of spliced leader associated retrotransposon in RNA interference-deficient Trypanosoma brucei (Patrick) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/930db893-65d6-4c21-84ac-e869a4184050/Screen+Shot+2024-06-10+at+6.47.37+PM.png Publications - The early macrophage response to pathogens requires dynamic regulation of the nuclear paraspeckle Azam et al., PNAS https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1586372789976-53FX379VLR3IH03CVP3V/Screen%2BShot%2B2020-04-08%2Bat%2B2.05.25%2BPM.jpg Publications - Rgg influences expression of multiple regulatory loci to co-regulate virulence factor expression in streptococcus pyogenes (Watson) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1585757341893-RINGRMORFZYD6ZOOFZGZ/Screen%2BShot%2B2020-04-01%2Bat%2B11.07.15%2BAM.jpg Publications - The histone variant H2A.Z promotes splicing of weak introns (Patrick) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1586371201070-RSFZQ006OOQINKP1GHBW/Screen%2BShot%2B2020-04-08%2Bat%2B1.20.04%2BPM.jpg Publications - Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway (Watson) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1585756841187-6LLJJ9QQ6QPKNQJ45LYH/Screen%2BShot%2B2020-04-01%2Bat%2B10.51.20%2BAM.jpg Publications - The splicing factor hnRNP M is a critical regulator of innate immune gene expression in macrophages West et al., Cell Reports https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/d75b0b3f-6275-4f3b-bdbd-d7b53e76a53c/Screen+Shot+2022-08-04+at+10.12.45+AM.png Publications - Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis Weindel et al., Cell https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1586372264223-BDFHSNM3MHQN5YUOWLEQ/Screen%2BShot%2B2020-04-08%2Bat%2B1.56.31%2BPM.jpg Publications - A MyD88-deficient mouse model reveals a role for Nramp1 in Campylobacter jejuni infection (Watson) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1585757717661-2E2ZU53GUNAVZTNE9HII/image-asset.jpeg Publications - For better or worse: cytosolic DNA sensing during intracellular bacterial infection induces potent innate immune responses Patrick, Bell et al., Journal of Molecular Biology https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/3a410a3f-0b3d-4b66-b05e-4b3f6e15b98c/Screen+Shot+2024-06-10+at+6.44.57+PM.png Publications - Serine/arginine-rich splicing factor 7 promotes the type I interferon response by activating Irf7 transcription Scott et al., Cell Reports https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1585756780290-VOWN18C1BBBVCZ3CM9IQ/Screen%2BShot%2B2020-04-01%2Bat%2B10.40.00%2BAM.jpg Publications - LRRK2 maintains mitochondrial homeostasis and regulates innate immune responses to Mycobacterium tuberculosis Weindel, Bell et al., Elife https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1586371674544-Y50OLXNBNGB3TF72GKH4/Screen%2BShot%2B2020-04-08%2Bat%2B1.47.00%2BPM.jpg Publications - Interaction of Campylobacter jejuni with host cells. (Watson) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/a594cabc-5c84-466c-a985-4d1cffee77b9/Screenshot+2025-04-10+at+4.22.45%E2%80%AFPM.png Publications - Necrosis drives susceptibility to Mycobacterium tuberculosis in PolgD257A mutator mice Mabry et al., Infection & Immunity https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/4b847fa2-ef62-4137-9818-8593d2cdce09/Screen+Shot+2023-01-05+at+1.38.17+PM.png Publications - SRSF6 balances mitochondrial-driven innate immune outcomes through alternative splicing of Bax Wagner et al., Elife https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/f64954c5-173a-4d43-95b1-d839a9521794/Screen+Shot+2023-04-18+at+7.22.30+PM.png Publications - Gasdermins gone wild: new roles for GSDMs in regulating cellular homeostasis Weindel et al. Trends in Cell Biology https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1585757987937-UTTG4TYPTRH1G76XGGRX/Screen%2BShot%2B2020-04-01%2Bat%2B11.19.00%2BAM.jpg Publications - Genetic interaction mapping reveals a role for the SWI / SNF nucleosome remodeler in spliceosome activation in fission yeast (Patrick) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/90aba03d-2b50-45d8-a22a-9b6181f41dfb/Screen+Shot+2024-06-10+at+6.49.57+PM.png Publications - Mitochondrial reactive oxygen species: double agents in Mycobacterium tuberculosis infection Ellzey et al., Current Opinion in Immunology https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1632242800030-RXW707GERWOTP8L3H29S/Screen+Shot+2021-09-21+at+11.40.11+AM.png Publications - The opportunistic intracellular bacterial pathogen Rhodococcus equi elicits type I interferons by engaging cytosolic DNA sensing in macrophages Vail et al., PLOS Pathogens https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1586373217517-WWRPQ6RTWXI36VCK0AGD/Screen%2BShot%2B2020-04-08%2Bat%2B2.12.27%2BPM.jpg Publications - Identification of Rgg-regulated exoproteins of Streptococcus pyogenes (Watson) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1591090761328-AQRWAG8121BT2TJCJEWM/Screen%2BShot%2B2020-06-02%2Bat%2B4.30.44%2BAM.jpg Publications - TRIM14 is a Key Regulator of the Type I IFN response during Mycobacterium tuberculosis infection Hoffpauir et al., Journal of Immunology https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1585757123433-9OMEDR4VB9J0XIW0G8PH/image-asset.jpeg Publications - Quantitative yeast genetic interaction profiling of bacterial effector proteins uncovers a role for the human retromer in Salmonella infection Patrick et al., Cell Systems https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/8522d39c-7ebc-4a4f-ae13-69201298e476/Screenshot+2025-09-30+at+7.47.39%E2%80%AFPM.png Publications - LRRK2 kinase activity restricts NRF2-dependent mitochondrial protection in microglia Weindel et al., Journal of Immunology https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/f6cd1b1b-349f-4e31-a2e0-a6aa99bc9d17/Screenshot+2025-09-30+at+7.46.25%E2%80%AFPM.png Publications - Plans within plans: post-transcriptional regulation governs macrophage responses Smith et al., Trends in Immunology https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1586372577555-G4IK1QK0AQJOR346P3IE/Screen%2BShot%2B2020-04-08%2Bat%2B2.02.14%2BPM.jpg Publications - Signal transduction in Campylobacter jejuni-induced cytokine production (Watson) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1629915305544-E4K1M4RMXHLTFSW1E84I/Screen+Shot+2021-08-25+at+1.14.41+PM.png Publications - Mitochondria: Powering the Innate Immune Response to Mycobacterium tuberculosis infection Patrick and Watson, Infection and Immunity https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1586370904871-QM9F0H06SB5CUP5OTMPT/Screen%2BShot%2B2020-04-08%2Bat%2B1.34.01%2BPM.jpg Publications - Distinct and overlapping roles for two Dicer-like proteins in RNA interference pathways of the ancient eukaryote Trypanosoma brucei (Patrick) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1586373093610-D7ABSGXDIO8VLSTS6PDK/Screen%2BShot%2B2020-04-08%2Bat%2B2.10.37%2BPM.jpg Publications - Role of tyrosine kinases and the tyrosine phosphatase SptP in the interaction of Salmonella with host cells (Watson) https://thepatrickwatsonlab.com/whatwedo daily 0.75 2023-01-27 https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/2b24c449-8b8a-4fdf-8759-acad0ed33d3b/Screen+Shot+2023-01-05+at+2.19.05+PM.png What we do - Make it stand out Mice harboring the LRRK2 G2019S mutation are susceptible to hyperinflammation during M. tuberculosis infection (from Weindel et al., 2022, Cell) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/d04534d7-792b-4f65-9095-294c054fa784/Screen+Shot+2023-01-05+at+2.29.36+PM.png What we do - Make it stand out RNA binding proteins in the SR and hnRNP families shape the innate immune transcriptome in murine macrophages in distinct and profound ways (from Wagner, Scott, West et al, 2021. Front Immunol.) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/dcd2aa33-8b58-4ee2-932e-7b4abeb4c094/Screen+Shot+2023-01-05+at+2.17.40+PM.png What we do - Make it stand out Localization of the pore-forming protein gasdermin D to the mitochondrial network following inflammasome activation in primary murine macrophages (from Weindel et al.., 2022, Cell) https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/354704a6-4136-45c5-92d1-8abd91e683ab/Screen+Shot+2023-01-05+at+2.16.45+PM.png What we do - Make it stand out The splicing factor SRSF6 is required to maintain mitochondrial homeostasis via controlling the alternative splicing of the apoptosis protein BAX (from Wagner et al., 2022, Elife) https://thepatrickwatsonlab.com/home daily 1.0 2025-04-11 https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/5159e37b-c8f3-49f8-b9f1-a01abc51cac4/Screen+Shot+2024-04-19+at+1.47.11+PM.png Home - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/0f887a5c-921b-49ff-b3d6-2a72695f0c82/Screen+Shot+2024-04-19+at+1.47.36+PM.png Home - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/aa6968d3-3bc8-4550-8e3a-e49e033809c4/Screenshot+2025-02-27+at+9.06.25%E2%80%AFAM.png Home - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1585759894644-1BHHWRVQ9TG66HLILTFB/Weindel%2C+Bell+et+al+IMAGE.png Home https://thepatrickwatsonlab.com/new-page daily 0.75 2023-01-27 https://thepatrickwatsonlab.com/people daily 0.75 2025-12-11 https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/77723460-725a-4fe7-bfe7-eb6067064c6c/Osborne%2C+Morgan+2.png People - Morgan Osborne, Ph.D. POSTDOCTORAL RESEARCH ASSOCIATE Vanderbilt Infection Pathogenesis and Epidemiology Research (VIPER) T32 Trainee B.S. James Madison University Ph.D. Joe Sorg; Texas A&M University Interests: I am interested in how mitochondrial stress shapes innate immune responses during nontuberculous Mycobacteria (NTM) species infections. https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1547160448959-R2Y41X24MP73FQJTZF6B/Image%2Bfrom%2BiOS.jpg People - Kayla Lopez Undergraduate Research Assistant P/W lab publications: Bell et al., mBio. 2021 CURRENT POSITION: M.P.H. student at Johns Hopkins University School of Public Health https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/240fcc70-ba0c-49dd-a557-969b317c9205/photo.jpg People - Mackenzie Smith GRADUATE STUDENT - VANDERBILT UNIVERSITY MOLECULAR PATHOLOGY AND IMMUNOLOGY NIH/NCI F31 Award recipient B.S. Baylor University Interests: I am interested in cancer-associated mutations in splicing factors and how they impact innate immune gene expression. LinkedIn https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1629910257394-1NB9PN7T9CON9Z8QSAS2/3082.jpg People - Sikandar Azam, Ph.D. POSTDOCTORAL REASEARCH ASSOCIATE P/W lab publications: Azam et al., PNAS, 2024. CURRENT POSITION: Research Scientist Columbia University https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/d7deaa5f-7817-41aa-96a8-a3301c41349c/Website+Picture+-+Stacy.jpg People - Stacy Hahn RESEARCH ASSISTANT B.A. Wake Forest University Interests: I am interested in how the interplay of mitochondrial homeostasis and intercellular pathogens affect host cell death outcomes and pathogenesis. https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1549131800093-HG22U67J62U1HK84DUWA/20190202_103610.jpg People - Krystal Vail, D.V.M. KVail@cvm.tamu.edu https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/e13f8f55-be8c-413e-beea-9e2ce029e219/IMG_20190603_170544_426.jpg People - Lily Ellzey GRADUATE STUDENT P/W lab publications: Ellzey et al., Curr Opin Immunology, 2023; Weindel, Ellzey et al., J Immunol. 2025. https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/2b2c0560-48c8-43c8-b5a5-33709dbb5b95/FB6A8598-027B-4D03-8F6C-83B8537B4AA8.jpg People - Andrew Dlugosch Undergraduate Research Assistant TAMU Biomedical Sciences Major, Class of 2025 https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/f941dae7-0b9e-46b1-ad9b-201f633e30de/KP+matches+a+car.jpg People - Kristin L. Patrick, Ph.D. kpatrick@medicine.tamhsc.edu https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1629922933549-MOSUF9EIQGHTIPXVREM2/image_from_ios.jpg People - Rhyston Broadhurst Undergraduate Research Assistant TAMU Biochemistry Major Class of 2024 https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/98972cee-6fc0-4f5a-b477-ea7012e0b2bb/E55B9DBE-B1AD-45C1-B1F0-C0503FD374A3_1_105_c.jpg People - Jessica Huskey GRADUATE STUDENT - VANDERBILT UNIVERSITY MICROBE-HOST INTERACTIONS Vanderbilt CBMS T32 Trainee B.S. Wake Forest University Interests: I am interested in histone modification and localization in the context of Mycobacterium tuberculosis infection and innate immune activation. https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/819899f1-c8a2-4151-8334-5f1e5aa1f4ac/IMG_20240530_140404.jpg People - Xinwei Geng, Ph.D. POSTDOCTORAL RESEARCH ASSOCIATE Ph.D. Songmin Ying, Zhejiang University Interests: I am interested in the mechanisms that govern genomic instabilities and the subsequent immune response, particularly in the context of infectious diseases https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/38ac95d0-5e67-4f1c-937e-5529c9fcbfb4/20190911_151134.jpg People - Timothy Fitzsimons, Ph.D. POSTDOCTORAL FELLOW Ph.D. John Boyce, Ph.D. Monash University https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/ad372684-6e33-4546-bcda-e27f7f13c8b6/IMG_4443.jpg People - Alyssa Miller UNDERGRADUATE STUDENT - VANDERBILT UNIVERSITY I am a sophomore from Chicago majoring in Medicine, Health, and Society with a minor in American Politics here at Vanderbilt. In the Patrick and Watson Lab, I am working with Mackenzie Smith on her research involving specific cancer-associated mutations within splicing factors, and their effect on gene expression and innate immune response. https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/b09f5a6c-6eae-4c03-bce3-23260d8d3a3b/IMG_0703+2.jpg People - Kayla Carmichael GRADUATE STUDENT - VANDERBILT UNIVERSITY MICROBE-HOST INTERACTIONS B.S. Xavier University of Louisiana Interests: I am interested in Mycobacterium tuberculosis pathogenesis and the impact of secreted virulence proteins on mitochondrial homeostatic processes and overall macrophage health. https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/41286384-56cf-49ec-9761-bfb78d013802/pic.jpg People - Savyasachi Dixit Undergraduate Research Assistant TAMU Bioichemistry Major, Class of 2024 https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1629910344993-UMZ4Y9YFK2SG3RGB1MMQ/Image%2Bfrom%2BiOS%2B%25285%2529.jpg People - Cory Mabry GRADUATE STUDENT, TAMU MEDICAL SCIENCES NIH/NIAID F31 Award recipient B.S. Texas A&M University Interests: I am interested in host pathogen interactions and how pathogens exploit the host’s immune system to prolong infection. I am working to understand how Mycobacterium tuberculosis regulates the host immune pathways through manipulation of pathways associated with inflammatory responses. https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1560186868247-C12ZK4ES5XRGZKAUMBA6/Image%2Bfrom%2BiOS.jpg People - Kaitlyn Carter Undergraduate Research Assistant P/W lab publications: Wagner et al., Front Immunology. 2021 CURRENT POSITION: GRADUATE STUDENT; TAMU Interdisciplinary Graduate Program in Genetics https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1629924615870-JYYZW0PJ2EEGO0PFUNTP/pam.jpeg People - Pamela Ulloa-Franco RESEARCH ASSISTANT/LAB MANAGER https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/68d30041-3453-4a5b-98ed-795e31336db3/IMG_1404.jpg People - Rylee King Undergraduate Research Assistant TAMU Biomedical Sciences Major, Class of 2025 https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1507606268539-F5I6ATJA78N92J5KZLP7/rob.jpeg People - Robert O. Watson, Ph.D., MPH robert.watson@medicine.tamhsc.edu https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/a45fd44d-00c2-4ef2-b349-fdf6cc50faea/IMG_3678.jpg People - Kaitlyn Armijo GRADUATE STUDENT - VANDERBILT UNIVERSITY MOLECULAR PATHOLOGY AND IMMUNOLOGY T32 IMSD Awardee B.S. Baylor University Interests: I am interested in nuclear paraspeckles and the role they play in regulating the innate immune response in macrophages. Linked In https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1547157580213-KT1BCHMU3GHMFACLYVRK/IMG_2866.jpg People - Hannah Wilson Undergraduate Research Assistant B.S. Texas A&M University CURRENT POSITION: Ph.D. student at M.D. Anderson https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1560188497370-0THF00Z5YJJ8Z7L86HVT/morgan.jpg People - Morgan Riba riba@medicine.tamhsc.edu https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1629910294438-SUFXP0VGXT3ZH9BOEE5A/Image%2Bfrom%2BiOS%2B%25285%2529.jpg People - Aja Coleman GRADUATE STUDENT, TAMU MEDICAL SCIENCES T32 IMSD Awardee NIH/NIAID NRSA F31 Diversity Fellow B.S. Trinity University Interests: I am interested in the pathways that influence host-pathogen interactions and the pathogenesis of MTB https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1507607004345-3YG7OR9GJBBH0693YBTU/IMG_1129.jpeg People - Caitlyn Hoffpauir cowen@medicine.tamhsc.edu https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/2bd22e73-f545-4793-ab9f-38e843012099/Newbolt_headshot.jpg People - Taylor Newbolt GRADUATE STUDENT - VANDERBILT UNIVERSITY MICROBE-HOST INTERACTIONS B.S. College of William & Mary Interests: I am interested in Mycobacterium tuberculosis and the role mitochondria, and mitochondria-associated proteins, play in regulating host immune cell responses to Mtb infection. LinkedIn https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1629928740563-G2UOFP3TGO50KY1APCQK/Screen+Shot+2021-08-25+at+4.57.10+PM.png People - Nicholas Babb RESEARCH ASSISTANT B.S. University of Arkansas-Forth Smith CURRENT POSITION: Associate Consultant Scientist at Eli Lily https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1634087897100-API4S1JMDTSN103O5V8R/Image+from+iOS+%282%29.jpg People - Michelle Tran Undergraduate Research Assistant TAMU Management Information Systems Major, Class of 2022 https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/75b74185-6f83-40b7-8c69-03b1931caec8/Photo+-+Jacob+Davis.jpg People - Jacob (Jake) Davis GRADUATE STUDENT: TAMU MD/PhD Program NIH/NIAID F30 Award recipient B.S. University of Oklahoma, Medical Humanities Scholars BA-MD Program Interests: I am interested in how interplay between infectious diseases and the immune system can determine disease outcomes. Specifically, I am interested in how Mycobacterium tuberculosis can manipulate innate immune pathways to evade host defenses and prolong infection. ORCID / LinkedIn https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/7b9398f5-dc4a-476c-8368-183806655ed9/Headshot+NHF.png People - Shreeti Amit Shreeti Amit https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1629910324130-52AGTS96ODG6QP1QN273/20210130_111429.jpg People - Eddie Martinez, M.S. GRADUATE STUDENT - VANDERBILT UNIVERSITY MOLECULAR PATHOLOGY AND IMMUNOLOGY NIH/NIAID NRSA F31 Diversity Fellow B.S. and M.S. University of Texas Rio Grande Valley Interests: I am interested in cell signaling, Immunology, and bioinformatics. https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1560188264652-G5GB2F6LUSV2QHUY50WL/Image%252Bfrom%252BiOS%252B%2525281%252529.jpg People - Haley Scott GRADUATE STUDENT, MEDICAL SCIENCES NIH/NIGMS NRSA F31 Diversity Fellow P/W lab publications: Scott et al., Cell Rep, 2024; Wagner, Scott et al., Front. Immunol. 2021 CURRENT POSITION: Scientist I Abound Bio https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1507607694326-BOV8DV9H8GAZ9C09DM1A/DSCF0004.jpg People - Chi Weindel, Ph.D. weindel@medicine.tamhsc.edu https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1529099351085-XOX0O2KQO50T8ZAPM5X3/Image+from+iOS.jpg People - Katie Grantham RESEARCH ASSISTANT/LAB MANAGER B.S. Texas A&M University CURRENT POSITION: D.O. candidate at Midwestern University https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/ef32a330-404c-4b06-9ffa-f012363e7cab/IMG_7241.jpg People - Morgan Chapman GRADUATE STUDENT: TAMU MD/PhD program B.S. Texas A&M University Interests: I am interested in understanding the role RNA plays in coordinating the immune response, to minimize immunopathology and immunocompromisation. My project looks at on how alternative splicing by the splicing factor hnRNPA2B1 affects the mobilization of Type I and Type II interferon responses to Mycobacterium tuberculosis. https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1629910396632-NRSHEYYSCV3S7EM89UUG/Screen%2BShot%2B2021-01-26%2Bat%2B12.35.13%2BPM.jpg People - Kelsi West GRADUATE STUDENT, TAMU Interdisciplinary Graduate Program in Genetics P/W lab publications: West et al., Cell Reports 2019; Wagner, Scott, West et al., Front Immunol 2021. CURRENT POSITION: Bioinformatics Scientist at Catalyst Data Sciences https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/9505f8e4-feb5-4f3e-a2b6-59adb229c8a8/Image+from+iOS.jpg People - Summer Apostalo Undergraduate Research Assistant TAMU Biology Major, Class of 2023 P/W lab publications: Scott et al., Cell Rep, 2024 https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1565707263604-IWU0WXLA6G60XPO1DGCB/IMG_2823.jpg People - Allison Wagner GRADUATE STUDENT, MEDICAL SCIENCES P/W lab publications: Wagner et al., Elife, 2022; Wagner et al. Front Immunol. 2021. CURRENT POSITION: Scientist I; Adverum Biotechnologies https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1634073633314-7G7SA9T939KQS84UUZOW/IMG_20210729_072730_538.jpg People - Emily Mulloy Undergraduate Research Assistant TAMU Biology Major Class of 2024 https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1507606896321-IGMBX4AKJQ3NV53J0PDD/IMG_1343.jpg People - Samantha Bell, Ph.D. bell@medicine.tamhsc.edu https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1547159559664-SE4EIP29KJ7GHJFPKNIE/Image%2Buploaded%2Bfrom%2BiOS.jpg People - Kendall Green UNDERGRADUATE RESEARCHER B.S. Texas A&M University https://thepatrickwatsonlab.com/about daily 0.75 2020-03-31 https://images.squarespace-cdn.com/content/v1/54061d7fe4b0ee7f1c8414eb/1411065567132-VGD301DKL385J7V5LTN0/empty.jpg About https://images.squarespace-cdn.com/content/v1/54061d7fe4b0ee7f1c8414eb/1411065567343-COSBYXA76IJZLF6IKXDT/front_large_basket.jpg About https://images.squarespace-cdn.com/content/v1/54061d7fe4b0ee7f1c8414eb/1411065566820-I90K019WV680JJMUBFYO/baby.jpg About https://images.squarespace-cdn.com/content/v1/54061d7fe4b0ee7f1c8414eb/1411065567100-8D2EGEUB65I36HIANNSH/both_baskets.jpg About https://images.squarespace-cdn.com/content/v1/54061d7fe4b0ee7f1c8414eb/1411065566959-GASF7FKFITM7VRRH6N66/bags.jpg About https://images.squarespace-cdn.com/content/v1/54061d7fe4b0ee7f1c8414eb/1411065566961-93I9WH8DAFU3AVXKGYAQ/back_small_basket.jpg About https://thepatrickwatsonlab.com/what-we-believe-in daily 0.75 2021-09-21 https://images.squarespace-cdn.com/content/v1/54c6a732e4b0f5f986bbff0c/1629926300222-67JJL34211DGR20MT70A/LabPoster_vCells.jpg What we believe in